HTHSCI 2H03 Lecture Notes - Lecture 21: Eosinophil, Interleukin 5, Salbutamol
2 May 2016
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Document Summary
Bronchioles contain smooth muscle that responds to inputs from the ans. Sympathetic input stimulates beta2-adrenergic receptors, relaxes bronchiole smooth muscle and increases lumen diameter, bronchodilation. The anatomy of the respiratory system offers a unique opportunity for targeting tissues pharmacologically using aerosols which use small particles of liquid or fine solid particles. : because we can target the tissue directly (essentially administering. Clinical consideration medications topically), we can limit systemic side effects. Advantageous because they can be used in emergency situations even when breaths are shallow: dry powder inhalers: day-to-day medications. These day-to-day type medications used in controlled situations. These medications require patient education as indicated above. Clinical considerations: inhaler adaptors can be used in children to help ensure proper administration. Air pollutants: tobacco smoke, ozone, nitrous and sulfur oxides, fumes from fluids or solvents, burning leaves. Allergens: pollen, grasses, weeds, animal dander, household dust and dust mites, mould.
