MEDRADSC 2X03 Lecture Notes - Lecture 3: Hydrogen Peroxide, Chemical Bond, Germ Cell
28 Jul 2019
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Document Summary
Lecture 3: the chemistry of radiation absorption by our cells. Effect mainly due to damage to biological macromolecule (ie. dna, rna, protein) (called critical targets) Target can be damaged by: radiation ( direct action , products or radiation interactions with other molecules ( indirect action ) Cytotoxic products (free radicals, h2o2) are produced when radiation breaks down water; cytotoxic products then migrate through cell to damage critical target. Bc of interaction with the water, a reactive free radical is produced. There is a chance that water can recombine if they are close enough & if another water molecule has been broken apart; its when they stay broken apart they are dangerous. Atom or molecule w unpaired electron in outermost orbit. Highly reactive chemically (very short lifespan); very reactive & unstable. Ion has a charge (not stable bc either missing or has an extra electron), free radicals have no charge but are still unstable (outer electron is not filled)
