PSYCH 2AP3 Lecture Notes - Lecture 17: Imipramine, Anxiety Disorder, Panic Attack
Document Summary
70% of people have panic attack from na lactate infusion in iv. Pet data from positive infusers: increase brain metabolism increase activity in non-dominant hippocampus. 50% have mitral valve prolapse (small problem in heart: thought to be genetic, can produce some symptoms of pd in non pd individuals: Etiology of pd: psychodynamic reoccurrence of separation anxiety. 20-50% of pd with agoraphobia had symptoms of separation anxiety as children imipramine blocks distress of separation in dogs and monkeys imipramine also most effective on pd imipramine also treats school phobia. Fear of embarrassment or humiliation in social/performance situations. 7% annual, 11% lifetime prevalence in us. Excessive or unreasonable fear of specific objects or situations. Phobia subtypes: animals, environment, blood/injection/injury - invasive medical procedures, situational - enclosed places, bridges, public transit, other - choking, vomiting, lycanthrophobia (fear of becoming a werewolf) 9% annual, 13% lifetime prevalence in us. 1:2 male to female ratio typical onset childhood - young adulthood.