PSYCH 2B03 Lecture Notes - Lecture 7: Birth Weight, Enteropathy, Tissue Transglutaminase
13 Aug 2020
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Definition: gluten sensitive enteropathy (inflammation of the gut) where the gliadin fraction of gluten (found in wheat and wheat-based products) causes a damaging immunological response in the small intestinal mucosa. Villi become progressively shorter then absent, leading to a flat mucosa. This results in malabsorption and can be demonstrated on a jejunal biopsy. The prevalence of coeliac disease is about 1 in 3000, but this may be a considerable underestimate. Tommy is a 9-month-old boy who is referred to the outpatient clinic. Uro- opens his bowels 4 times a day. General miserable and tired for the past couple of months. Birth his birth weight was 3. 17kg he gained weight well initially. Feeding weaned off milk at 6 months. Developmental milestones have been reached smile 6 weeks and sit 6 months. His father has crohn"s disease, for which he has required several operations. Growth and weight- as mentioned above and also has been failing to gain weight age.
