PSYC 2800 Lecture Notes - Lecture 10: Common Ethanol Fuel Mixtures, Aspirin, Enzyme Inhibitor
18 Dec 2016
School
Department
Course
Professor
Document Summary
Dose-response relationship = correlation between the response and the quantity of drug administered: this is a strong demonstration of the specific effects of a drug. Threshold = the dose at which an effect is first observed. Some response systems have higher thresholds than others, so dose-response curves can be created for different drug effects. Some drugs have an all-or-none dose-response relationship: seizures. Effective dose = the dose of a drug that produces a meaningful effect in some percentage of test subjects: ed50 refers to the effective dose for half the animal subjects in a drug test. Lethal dose = the dose of a drug that has a lethal effect in some percentage of test subjects: ld50 refers to the lethal dose for half the animal subjects in a drug test. Therapeutic index = ld50/ed50: always greater than one. Potency is measured by the amount of a drug required to produce a given effect.
