ANAT 216 Lecture Notes - Lecture 1: Subclavian Vein, Cytotoxic T Cell, T Helper Cell
28 Apr 2018
School
Department
Course
Professor
ANAT 216 week 1 lecture 1
Lymphatic sys
Function
Help cardiovascular and immune sys
Transports lymph (maintains normal blood V), prod, maintains and distributes
lymphocytes (blood V would drop w/o it)
Provide an alt route for hormones, nutrients and waste prod
components
Lymph vessels, lymph (Interstitial fluid that enters lymphatic vessel), lymphoid
cells/tissues/organs
Lymphatic
vessels
Lymphatic
cap
b/n tissue cells and blood cap, endothelial cells overlap and are
anchored down via collagen fiber bundles, need to be anchored bc
high P outside would collapse vessel, act as one way swinging door
(door closed when volume and pressure is greater inside the cap)
Lymphatic
collecting
vessel
One way twrds heart, have more valves than veins to compensate
for the low pressure, fluid mvmt due to skeletal muscle
contraction
Lymph
trunks
Lumbar (lower limbs), bronchomediastinal (thoracic wall, lung,
heart), subclavian (upper limbs), jugular (head, neck), intestinal
(stomach, intestines, spleen, pancreas, part of liver)
all collect lymph from a specific region
Lymphatic
ducts
Right: accepts lymph from R limb, thorax and head above
diaphragm, returns to venous circ at the junction of the R internal
jugular and subclavian vein
Thoracic duct: starts at 1st two lumbar vertebrae, main return of
lymph from both side of the body below the diaphragm and L side
of upper body, returns to venous circ at the L subclavian vein near
junction w L internal jugular vein
Cisterna chyli: start of duct, accepts lymph form lumbar and
intestinal trunks
lymphoid
cells
Macrophages: 1st line of defense, target and attack an antigen
Lymphocytes: 1st line, originate from stem cells in RB marrow
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Transports lymph (maintains normal blood v), prod, maintains and distributes lymphocytes (blood v would drop w/o it) Provide an alt route for hormones, nutrients and waste prod components lymph vessels, lymph (interstitial fluid that enters lymphatic vessel), lymphoid. One way twrds heart, have more valves than veins to compensate for the low pressure, fluid mvmt due to skeletal muscle contraction. Lumbar (lower limbs), bronchomediastinal (thoracic wall, lung, heart), subclavian (upper limbs), jugular (head, neck), intestinal (stomach, intestines, spleen, pancreas, part of liver) all collect lymph from a specific region. Right: accepts lymph from r limb, thorax and head above diaphragm, returns to venous circ at the junction of the r internal jugular and subclavian vein. Cisterna chyli: start of duct, accepts lymph form lumbar and intestinal trunks. Macrophages: 1st line of defense, target and attack an antigen. Lymphocytes: 1st line, originate from stem cells in rb marrow. T cells: leave bone marrow thymus, cell mediated immunity, manage immune response.
