BIOL 103 Lecture Notes - Peptic Ulcer, Gastrin, Parietal Cell

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Biology lecture #3 regulation of digestion system. Topics to be covered regulatory physiology, pioneering discoveries, the peptic ulcer. Gastric glands lining stomach produce pepsin in an inactive form called pepsinogen, and this combined with hydrochloric acid becomes pepsin. Cells that line the stomach produce a mucous that has a ph of 6 that protects against the acid. Control of muscular and glandular activity by local nerves. Secreted mainly be cells that are in the epithelium of the stomach and small intestine that tend to directly affect those organs. Gastrin secreted by stomach in response to a meal that stimulates muscle contraction and acid production, returns to stomach via blood. Pathology associated with the defective protein is that the secretion of mucous is thick and sticky, and therefore has much effect on body such as not being able to clear the mucous.

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