HLTH 101 Lecture Notes - Lecture 4: Low Birth Weight, Coronary Artery Disease, Prenatal Nutrition
12 Dec 2017
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Relationships bewteen an exposure at one point in the life course and health outcome years or decades later, irrespetive of intervening experience. The dutch famine, or hungerwinter, started in november 1944 carried on until may: rations were as low as 400-800 calories a day. Less than a quarter of the recommended adult caloric intake. The cohort: children born shortly before, during , and immediately after the famine. The study objective: to investigating the effects of exposure to famine on health in adulthood. Results - in later life (the latent effect) 3-fold increase in coronary heart disease prevalence among the cohort. People conceived in famine had a higher blood pressure rise under stress. Famine children"s children were also born smaller than average. The study of the ways in which the environment alters the expression of genes . Environmental factors like diet, stress, prenatal nutrition make an imprint on genes that is passed on to the next generation.
