BISC 101 Lecture Notes - Lecture 22: Electrochemical Gradient, Resting Potential, Action Potential
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25 Jun 2017
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To define membrane potential: distribution of the positive and negative charges across a membrane, measure in mv, concentration of charges inside a cell relate to outside a cell. To describe how potential is generated (be able to draw and label the action potential graph: resting potential neuron is polarized. K+ flow out: chemical gradient is built by active transport by na+/k+ pump, 3na+ out. 2k+ in with help of atp: k+ diffuses out do(cid:449)(cid:374) its (cid:272)o(cid:374)(cid:272)"(cid:374) gradient, inside becomes negative and outside becomes positive negative inside attracts the k+ back into membrane, electrical gradient slows the. 70 diffusion of k+ out of the cell b/c inside of membrane becomes ve, K+ ions are attracted back, this counteracts movement of k+ ions out, k+ on outside and inside become equal = no net movement of k+ To explain the effect of multiple synapses: esps make action potentials more likely in postsynaptic cells depolarization, na+ inflow.
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