CRIM 101 Lecture Notes - Lecture 6: Twin Study, Bad Hindelang, Monoamine Oxidase A

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Studying human genetics can be difficult from an ethical, numerical, biological perspective. Good scientific studies require a large number of identical research subjects. Cannot (ethically or legally) clone identical humans as research subjects. Even large scale studies (e. g. , drug trials) are influenced by biological factors and environmental factors (diet, lifestyle) Clones do exist, in the form of twins. Dizygotic (dz) twins result from 2 sperm fertilizing 2 eggs ( no more genetically similar than any other pair of full siblings ) Monozygotic (mz) twins result from a single sperm fertilizing single egg, which then cleaves & becomes 2 separate zygotes. Single sperm fertilizing single egg (2 genetically identical babies) Share 100% of the 1% of dna that explains variations in characteristic. Result from 2 sperm fertilizing 2 eggs (no more similar than any other full siblings) Share 50% of the 1 % of dna that explains variation in characteristics.

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