BIOL201 Lecture Notes - Lecture 18: Protein Kinase, P53, Histidine

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Carcinoma 90% of all cancer, arise from epithelial cells that cover external and internal body surfaces. Sarcoma develop from supporting tissue such as bone, cartilage, fat, and muscle. Cancer is an abnormal type of tissue growth. Crucial issue is not the rate of cell division, but the balance between cell division and cell death. Cell differentiation is the process by which cells acquire the specialized propertied that distinguish types of cells from each other. As a cell acquires this trait, they generally lose the capacity to divide. Benign in a confined local area and are rarely dangerous. Malignant capable of invading surrounding body tissues, entering the bloodstream, and spreading to distant parts of the body. Cancer cells do not have to be anchored to a solid surface in order to grow (anchorage-independent growth) If a normal cell is prevented from using integrins, division is stopped and apoptosis.

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