NURS 216 Lecture Notes - Lecture 28: Septic Shock, Meropenem, Cefotaxime

• School: University of Alberta
• Department: Nursing
• Course: NURS 216
• Professor: Helena Schaefer

Document Summary

Anticholelithic drugs: decreases cholesterol reabsorption, synthesis and increases emulsification. Most common source of pathogens: endogenous patient flora staphylococcal (gram +) streptococcal and streptococci (gram +: coli (gram -) Signs and symptoms infection tachycardia fever abdominal pain. Cephalosporin cefazolin cefotaxime, ceftriaxone, e. coli efficacy. Penicillin allergies may also lead to cephalosprin allergies. How to treat a suspected infection: find where the infection is located based on health history and focused health assessment findings. Pqrst antibiotic empiric treatment based on suspected bacteria no antibiotics may also be prescribed based on further evidence started asap: diagnostic tests bacterial versus viral (e. g. gram staining) Drug to drug interactions (e. g. oral contraceptives, nsaids) Epithelial cells: barrier of entry, secretes antimicrobial enzymes. Phagocytic neutrophils and macrophages (opsonins: tag microbes for easier recognition) Dendritic cells (leukocytes) trigger immune response cytokines secreted + more lymphocytes, macrophages, complement system activated stimulate inflammation, chemotaxis and phagocytosis. Cytokines: interferons, interleukins produced by human leukocytes in response to viral infections.