NURS113 Lecture Notes - Lecture 8: Angiotensin-Converting Enzyme, Afferent Arterioles, Hypertensive Heart Disease
19 Apr 2017
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Co (blood ejected from each ventricle / minute) = sv x hr. Sv (blood ejected from each ventricle / contraction) = edv (before contraction) esv (after contraction) Map = diastolic + (1/3) pulse pressure, co x vr (good indicator of tissue perfusion) Resistance: viscosity (polycythemia, dehydration, vessel length (obesity, vessel radius. Adh / vasopressin (hypothalamus detects water loss, pituitary releases adh, causes kidneys to retains water) Anp secreted by atria in response to high blood volume, targets kidneys and decreases. Na+ reabsorption, it also vasodilates afferent arteriole in nephron. Primary (w/o another disorder: age, race, diet/alcohol, lifestyle, salt intake, smoking, target-organ damage, stroke, dementia, cad, mi, angina, lv hypertrophy, congestive heart failure, renal ischemia, retinal ischemia, exudate. Secondary (w/ another disorder: kidney disease, hormonal disorder, coarctation of aorta. Sp (blood pools, venous valves close) compensate by vasoconstriction, hr: acute, maybe b/c of drugs, immobility, diuresis, venous pooling, chronic, secondary to disease (dm, adrenal insuficiency), idiopathic, aging.
