BIOL 241 Lecture 24: Notes theme4a
Document Summary
Hannah was born with a very small, under-developed jaw and her thumbs did not bend; elbows/wrists did not rotate properly; hearing loss. Dr. f. bernier: sequenced hannah"s genome and discovered the mutaion that eluded scienists for more than 60 years. Nager syndrome: haploinsuiciency of the spliceosomal factor sf3b4. Selective breeding -how is this variaion inherited; transmission geneics. Test crosses: when dominance isn"t so simple. A couple of theories of inheritance from the mid 1800s: Blending inheritance: ofspring have traits that are intermediate to their parents". Lamarck: inheritance of acquired characters in other words, favourable traits acquired by parents are passed on to ofspring directed evoluion. Gregor mendel (1822-1884) tested hypothesis of blending vs. pariculate inheritance used true-breeding varieies of peas: many varieies with diferent characters. Determine whether staisical paterns in the occurrence of the contrasing traits persisted by means of crossing.