BIOL 243 Lecture 6: THEME 2C Translation and Protein Structure

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17 May 2016
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Composed of an amino group (nh2) and carboxyl group (cooh) bonded to a central carbon atom. Amino acids link together by covalent peptide bonds - from amino to carboxyl. The bond goes between the carboxyl and amino group, created by a dehydration reaction. Polypeptides are long chains on amino acids, linked by peptide bonds. The r-group (aka. side chain) located on the same side as amino group, is variable and determines characteristics of amino acids (whether if the r-group is hydrophobic or hydrophilic. A polar side chain is hydrophilic - water is polar too). 1. nonpolar (hydrophobic) amino acids r-group contains -ch2 or ch3. 2. aromatic amino acids r-group contains carbon ring with alternating single- double bonds. 3. charged amino acids r-group contains acids or bases that can ionize. 4. uncharged polar amino acids r-group contains o2 or oh. Special function amino acids: methionine every polypeptide begins with this, proline causes bends in polypeptide chains, cystine disulfide bridge that links different polypeptides together.

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