BIOL 331 Lecture Notes - Lecture 9: Transfer Rna, Aromatic Amino Acids, Inverted Repeat
23 Feb 2015
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Document Summary
Holoenzyme has all subunits required to carry out function. Core enzyme doesn"t have all subunits. There are different names for the alpha subunits: alpha-1 makes extensive contact with the beta subunit, alpha-2 makes extensive contact with the beta prime subunit. No matter which type of cell, all will have similar structures / subunits. Major difference between prokaryotes and eukaryotes: one rna polymerase can transcribe all types of rna in prokaryotes (e. g. mrna, trna, rrna, three rna polymerases are required for eukaryotes. Rna pol i: 18s + 28s rrna. Rna pol iii: 5s rrna + trna. Beta and beta prime subunits are called pincers, because the rna pol structure looks like a crab claw -> pincers can open and close. Open structure is shown on the left when it"s open, dna will bind in this pocket (lets the promoter in and then encircles it) Eukaryotic version has different names for subunits, but has a similar structure to the prokaryotic version.
