CMMB 403 Lecture Notes - Lecture 13: Maternal Effect, Kk Mzt Skopje, Fallopian Tube
9 Oct 2018
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Concept of the day: the mid-blastula transition (mbt) Transcription of the zygotic genes begins (this aspect is also called the maternal to zygotic transition, or mzt) The cell cycle lengthens, gap stages are added. The synchronicity of cell division is lost. Characteristic of early development that is different for all species. Not in middle of blastula, mbt just makes it happens during the blastula phase. Mzt: going from controlled development (using maternal cells to guide development) to self development. Cell cycle (from mbt) lengthens and gap stages (g1, g2) are added. During early cleavage, there is rabid cell division so there is no need for gap stages before mbt, embryo skips gap stages, only does m and s phase. Side effect of transition: lose synchronicity of cell division (all cells are not dividing at the same time, as they do during cleavage) A comparative overview of the mzt in several model organisms.
