CMMB 431 Lecture Notes - Lecture 19: Legionella, Obligate Aerobe, Mortality Rate
25 Jun 2020
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No person to person spread, was airborne. Bio lms growing in water cooling towers in tops of building. People tracked down infectious agent and studying it became a big priority. Named because it was rst noted to cause disease among legionaires. Branched chain fatty acid rich cell wall. Slow growing organism compared to other lab microorganisms. Fastidious organism, so need to supplement with amino acids and iron. Lower respiratory tract: lower than middle of neck. Mortality rate depends on outbreak and cohort. Disease that still results in outbreaks from time to time. Around 100 cases per year in canada. Named for city it was rst identi ed in. Self limiting: don"t need medical intervention for patient to get better, don"t know if it includes transmission. Legionella can replicate in amoeba, which love to graze on bio lms but growth inside amoeba changes virulence.
