NURS 503 Lecture Notes - Lecture 2: Cerebrovascular Disease, Cholinesterase, Mediterranean Diet

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Lancet, 390, 2673-2709. dx. doi. org/10. 1016/s0140- 6736(17)31363-6 (up to care and support heading on p. 2709) Dementia and mild cognitive impairment are characterized by a decline from a previously attained cognitive level, but in dementia in contrast with mild cognitive impairment, the decline affects activities of daily living or social functioning. Population attributable fraction (paf)= the percentage reduction in new cases over a given time if a particular risk factor were completely eliminated. Some modifiable risk factors include peripheral hearing loss and social isolation. Modifying risk factors could translate into a large effect on the global burden of dementia. While modifying risk factors will not delay, prevent, or cure all aspects of dementia- it may push back the onset. Interventions like using antihypertensives, eating a mediterranean diet, cognitive interventions like stimulating brain activity, physical activity and exercise, and social engagement. P(cid:396)ecli(cid:374)ical alzhei(cid:373)e(cid:396)"s disease occu(cid:396)s whe(cid:374) the(cid:396)e a(cid:396)e ea(cid:396)ly alzhei(cid:373)e(cid:396)"s pathoge(cid:374)ic changes but no memory impairment.

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