BIOC 2580 Lecture Notes - Lecture 1: Hydrogen Bond, Amine, Myoglobin

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Of our bodies is made up of only 6 elements: oxygen, carbon, hydrogen, nitrogen, calcium, phosphorous: oxygen is the most abundant in the human body by weight b/c cells are made up of 65- Small molecules: sugars, amino acids, nucleotides, carboxylic acid derivatives, acts as building blocks for macromolecules. Macromolecules: proteins chains of amino acids, polysaccharides chains of simple sugars, nucleic acids chains of nucleotides. Myoglobin is a protein that we have in our muscles that stores oxygen in muscle tissue. Made of carbon, nitrogen, oxygen and sulfur. Most proteins: 10 000 to 100 000 g/mol. Protein size is expressed in kilodaltons (kda: 1 dalton (da) = 1 g/mol (molar mass of hydrogen atom, 1 kda = 1000 g/mol. Myoglobin is 16. 5 kda small protein. Similar building blocks are bonded to form bigger structures. These simple bonds are amide bonds, ester bonds, etc. By understanding the building blocks we can understand the macromolecules.

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