BIOC 4580 Lecture Notes - Lecture 24: Cytosine, Diglyceride, Catalase
14 Mar 2017
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Document Summary
Attachment of fatty acid(s) to backbone through ester or amide linkage. Addition of hydrophilic head group to backbone through phosphodiester linkage. Transport to membrane or tissue of choice: overview. Differences & similarities, in lipid composition & synthesis of prokaryotic & eukaryotic membranes. Recall the species & tissue differences in weight bercentages of total lipid. Ps, pc and pe will be our focus in mammalian systems, as well as pa as it is a main precursor for a lot of these lipids. Prokaryotes and eukaryotes (yeast & mammals) have slightly different but some overlapping strategies for phospholipid synthesis. Head group attachment is via the phosphodiester bond. Dag + phosphoric acid + alcohol head group glycerophospholipid. In eukaryotes, lipid synthesis occurs using cytosolic and er membrane-bound enzymes and involves subsequent trafficking. Incorporation of fas into membrane lipids takes place on er membranes & steps are catalysed by membrane- associated enzymes.
