BIOL 1090 Lecture Notes - Lecture 21: Microtubule Organizing Center, Axoneme, Tau Protein
Document Summary
Vacuolar membrane contains active transport systems that generate high interior ions. Cytoskeleton- dynamic network of connected lamentsand tubes that extend. 1. structural support: special organizationn within the cell, intracellular transport. Microtubules(medium): a hollow tube formed from tubulin dimers. Intermediate laments(largest): a strong bre composed of intermediate subunits. Has 2 major types, axonemal mt, and cytoplasmic mt. Part of structures (axoneme) involved in cell movement. *alpha and bata tubular bind together, never aa or bb. There is a - end and a + end. Aligned in the same direction- head to tail. Mt"s have a fast-growing + end and a slow growing - end. Structural polarity is important for the mt growth/shrinkage and direction of movement of material along mt. Dynamic instability- this leads to rapid turnover of most microtubules. Catastrophe(this is a normal thing)-shrinkage can occur vary rapidy at the + or - end. Microtubule organizing center- mtoc- center cite of microtubule assembly.