BIOL 1090 Lecture Notes - Lecture 10: Five-Prime Cap, Microrna, Polyadenylation

• School: University of Guelph
• Department: Biology
• Course: BIOL 1090
• Professor: Andrew Bendall

Document Summary

Can have 2 barr bodies if cell had xxx (metafemales!) The nature of the gene & its expression: transcription, gene = a transcribed region of dna and its promoter region (if not transcribed --> intergenic region!) Codes for one of many types of rna! Snrna (small nuclear)/ rrna (ribosomal)/ trna (transter) / pre- mirna (regulates transcription)/ etc: steps: Dna --transcription--> rna --process/stabilize--> mrna --translation--> protein --post- translation--> function: rna vs dna. Rna uses uracil (pyrimidine) instead of thymine. Rna pentose sugar = ribose, not deoxyribose. Rna is also synthesized from 5" to 3" direction! Synthesized from a template/coding strand on dna (one of the double strands) Reads dna from 3" to 5"! (so that rna is 5" to 3"!: transcription bubble = where dna double helix is locally unwound. Where rna polymerase makes contact after binding. A & t because easiest to unwind! (only 2 h-bonds instead of. Transcription starts @ +1 sequence! (downstream = +)