BIOL 2400 Lecture Notes - Lecture 14: Genotype Frequency, Natural Selection, Zygosity

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We can now estimate the change in allele frequency at the a locus, due to the differential reproduction of the genotypes genotype frequency. W aa relative fitness w i contribution to the next generation. W aa f(aa) x w aa f(aa) x w aa f(aa) x w aa. We estimate the average fitness of the population as: We estimate the new frequency of the a and a alleles as: p" = [f(aa) x w aa ] + [f(aa) x w aa ] / w q" = [f(aa) x w aa ] + [f(aa) x w aa ] / w also: W = 0. 360 + 0. 432 + 0. 128 p" = [0. 360 + (0. 5 x 4. 32)] / 0. 92. = 0. 374 f(a) increased, f(a) decreased as expected based on the relative fitness of genotypes. Aa homozygotes have the highest fitness (w aa = 1)

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