BIOL 2400 Lecture Notes - Lecture 4: Inbreeding Depression, Adult Stem Cell, Quantitative Genetics
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Terminology: gene a sequence of dna transcribed into rna (e. g. ester, allele a sequence variant at a genetic locus (e. g. esterl), mutually exclusive alternative states for a. Scaling mendel to the level of evolution population genetics. Evolution happens at the population scale: population, groups of interacting and potentially interbreeding individuals, changes in the frequency of traits in a population can be tied to changes in the frequency of alleles. Evolution from a population genetics perspective: changes in allele frequencies across generations. Total = 200 alleles: 100 individuals, 36 aa individuals = 72 a alleles, 48 aa individuals = 48 a alleles and 48 a alleles, 16 aa individuals = 32 a alleles. Gamete production and fertilization do not change allele frequencies. In the absence of outside forces, the allele frequencies of a population will not change: assumptions. Large population: no selection, no migration, no mutation.