BIOL 2400 Lecture Notes - Lecture 7: Molecular Evolution, Base Pair, Qi

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Phylogeny 2 finding synapomorphies in dna sequence data choosing the shortest tree parsimony vs. maximum likelihood gene trees vs. species trees. Maximum parsimony with dna (simplest explanation) if the two branches have the t sub. , then the ancestor also did (maximum parsimony) Primate phylogeny based on 10 200 bp of pseudo hemoglobin gene (only 15 sites are useful: maximum parsimony, alternative trees require more steps. Purpose of outgroups are to identify ancestral character state: we are only using 3 of the above 15 sites! pseudo hemoglobin gene parsimony informative sites (3 of 15) Parsimony informative sites (pi) a base position site that has at least two different bases that are each present in at least two different species (taxa) parsimony principle changes. : the tree with the minimum number of hypothetical evolutionary: here: mutations from one base pair to another is the preferred tree.

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