HK 2810 Lecture 3: 3

• School: University of Guelph
• Department: Human Kinetics
• Course: HK 2810
• Professor: Kerry Ritchie

Document Summary

--> we have 2 major routes to communicate & coordinate our body functions. > secretory cell releases hormone hormone is in extracellular space diffuse into blood (stream) *cell receptor dictates how target cell responds not the hormone, carried in blood stream to target tissue. ==> hormone recognizes the target tissue b/c of the specific membrane receptor population. ==> receptors can be on the plasma membrane (nls non lipid soluble hormones) or they could be cytosolic (intracellular ls (lipid soluble hormones) ) ==> very sensitive system hormones circulate in very low [conc. ] ** amplification thru those g-protein cell signaling cascades. > another one = parathyroid hormone (ca2+ levels) Stored in secretory vesicles prior to release. Requires plasma membrane receptor on target tissue (nls can"t just diffuse out: metabolites of amino acids (amines) Epi and ne, dopamine, serotinin, thyroid hormone (ls) Nls stored in secretory vesicles prior to release. Nls - require plasma membrane receptor on target tissue.