HK 4550 Lecture Notes - Lecture 3: Chronic Obstructive Pulmonary Disease

• School: University of Guelph
• Department: Human Kinetics
• Course: HK 4550
• Professor: Jeremy Simpson

Document Summary

No rbc"s (clear substance) separated from the blood by the blood brain barrier capacity (protein is the buffering capacity in your blood) (cid:224) this is a good thing more sensitive (detect small changes in ph easier: lower buffering capacity means that changes in csf ph for a given change in pco2 is greater than it is in the blood, lots of carbonic anhydrase (cid:224) if h+ and bicarb aren"t getting to the csf how will you change the ph of csf (cid:224) need to use co2 and get them through indirectly with lots of ca (convert into. Wakeful drive or basal ventilation (flat line at bottom of curve) for a given change in pco2 there is no responsive changes in co2 (no increase or decrease in ventilation) pco2 is not driving need to breathe: not responsive to changes in co2, non chemoreflex, not affecting drive to breathe.