MICR 2420 Lecture Notes - Lecture 18: Trichoderma Harzianum, Myxoma Virus, Delta Endotoxin

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Use of microbe to control growth of another. Introduce agent organism into new ecosystem to naturally prey on pest organisms. A predator that eradicates its food course doesn"t survive! Efecive for farming, but not for disease control. Target: pest whose populaion is suppressed by agent, the prey. Case study examples: explosive rabbit growth suppressed with virus. Produces proteins that interfere with host immune system (especially caspases) Lumps (myxomata) and puiness around head and genitals. Loss of appeite, listless, fever, death within a few days. Tried to introduce spanish rabbit lea to help spread of virus. Produces crystalline toxin drying sporulaion (delta endotoxin that is protecive to plant) *more speciic the agent, more controlled the intervenion and fewer unintended consequences. Expressed by plant, has natural resistance to insects. Controversial in food crops, but common in texile crops like coton. Resistance is common, secondary pest infestaions can occur: fungus protects food. Atack and kill wide range of fungi.

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