NUTR 3070 Lecture Notes - Lecture 9: Retinoic Acid Receptor, Basal Metabolic Rate, Niacin
22 Jan 2020
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Document Summary
Traditional micronutrients fat soluble vitamins, water soluble vitamins, and minerals. Micronutrients that control type ii steroid hormone receptors and have major global health implications (vit a, d, k, calcium, phosphorous and fluoride) Micronutrients that work together in oxidant defense (vit e, c, selenium, niacin, riboflavin, copper, zinc, magnesium) Micronutrients that act as enzyme cofactors (vit b6, b12, niacin, thiamin, folate, biotin, pantothenic acid) **1 out of 3 people in developing countries are affected by vitamin and mineral deficiencies. Iodine used to make t3 hormone, which regulates synthesis of proteins that control basal metabolic rate. Steroid hormone receptors (shrs) intracellular protein receptors that bind ligands and become active transcription factors. Two types: cytosolic receptors respond to steroid hormones like estrogen, testosterone, progesterone, glucocorticoids and mineralocorticoids, nuclear receptors respond to steroid and non-steroid ligands, like thyroid hormone, retinoic acid and calcitrol. Iodine (inorganic mineral) contents of most foods is low.
