PATH 3610 Lecture Notes - Lecture 3: Ibuprofen, Seminiferous Tubule, Pneumonia (Non-Human)

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amethystturtle619

12 Dec 2016

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Document Summary

Complement = things that enhance the ability of antibodies and phagocytic cells to clear microbes and damaged cells. Its appearance will depend on the extent of each of these processes, and to some degree is related to the type of agent, which caused the response. Chronic inflammation can arise from an acute inflammatory response that hasn"t eliminated the original causing agent, or can occur without an obvious acute phase. The desired outcome of chronic inflammation, or of any injury, is for healing and repair to occur, so that the integrity and function of the injured tissue is restored if possible. The term inflammation implies a complex, predetermined and nonspecific response to injury, consisting of a microcirculatory response as well as mobilization of phagocytic cells; this is also termed the acute inflammatory response. Acute inflammatory response is characterized by: redness, heat, swelling, pain, loss of function.

Related Questions

1. Diseases are those abnormal conditionsin which the bodys defensive cells fail to make the self versus thenonself distinction correctly, and attack the body's owntissues.
A. Cancerous
B. Septic
C. Autoimmune
D. Nondiscrete

2. Which of the following determinesgenetic sex (male or female) in mammals?
A. the acrosome of the sperm
B. the temperature of the developing fetus
C. the SRY gene on the Y chromosome
D. the genetic makeup of the parents
E. the Y chromosome contained in the egg

3. Which of the following regardingantigens is true?
A. Antigens can only be recognized by their specificity.
B. An antigen is a molecule which promotes a general immuneresponse.
C. A large antigen is likely to have many different epitopes, eachof which can stimulate a distinct immune response.
D. The most effective antigen are small simple amino acidcomplexes.
E. Bacteria do not contain antigens.

4. All of the following are defensemechanism employed by vertebrates except

A. negative test, as in, not findingself-markers.

B. change in chromosomal composition

C. positive test to recognize presence ofnonself-markers

D. specific antibodies.

E. skin and mucous membranes asbarriers.

5. The immune system depends on thefunction of ______, which include several types of phagocytic cellsand two kinds of lymphocytes.

A. platelets

B. leukocytes

C. target cells

D. erythrocytes

6. In comparing the kidneys of marine andfreshwater fish, which of the following is not true?

A. Freshwater fish fluids have a greaterosmotic concentration.

B. Marine fish excrete many of the divalentcations through the anus.

C. The flow of the filtrate is faster inmarine fish.

D. The urine is less concentrated infreshwater fish.

E. Marine fish drink greater quantities ofwater.

7. The kidneys of which one of thefollowing are so highly efficient that it never has to drink waterand can obtain all of its water from its food?

A. desert lizard

B. camel

C. pocket moue Perognathus

D. kangaroo rat

E. gerbil

8. Select the incorrect statement regardingthe temperature of the immune system.

A. Interleukin-1 is a pyrogen, which cancause the neurons in the hypothalamus to raise the body'stemperature, producing a fever.

B. Fevers cause the liver and spleen tostore sodium and potassium which bacteria need for their growth andmetabolism.

C. Fevers above 105 Â° F can be fatal.

D. Fever contributes to the body's defensesby stimulating phagocytosis.

E. When macrophages encounter invadingcells, they release interleukin-1, which is carried to the brain bythe circulatory system.

9. Which of the following is not amechanism to prevent polyspermy?

A. change in membrane otential of egg

B. vitelline envelopes lift off surface ofegg

C. sperm nuclei degraded inside eggallowing one to fuse

D. cortical granule enzymes remove spermreceptors from egg

E. altering composition of exterior eggcoat

10. Which of the following cells have anincorrect function?

A. neutrophil---important antigenpresenting cell

B. eosinophil---important to theelimination of parasites

C. mast cell---releases histamine

D. macrophage---phagocytic cell

E. monocyte---precursor of macrophage

11. Which part of the antibody moleculedetermines its role in the immune response?

A. disulfide chains

B. the entire molecule

C. the stem of the Y

D. the heavy chains

E. two arms of the Y

12. Select the incorrectly matchedimmunoglobin (Ig)subclass and a fact about it.

A. IgG---found in the plasma and secretedin secondary response

B. IgM---first secreted during primaryresponse

C. IgE----promotes the release ofhistamine

D. IgA----found in saliva and motherÃ¢â¬â¢smilk

E. IgD----serve as receptors on thesurfaces of T cells

13. _______ are the source ofantibody-producing cells.

A. B cells

B. Plasma cells

C. Monocytes

D. Macrophages

E. T cells

14. Select the incorrect statementregarding the inflammatory response.

A. The alarm signals can be histamines orprostaglandins.

B. The inflammation response is a localizedspecific response to infection or injury.

C. Neutrophils spill chemical in the areaof injury or infection that kills bacteria, tissues, andthemselves.

D. Tissue can exhibit edema from thedilation of the blood vessels in the area of injury orinfection.

E. If a cell is injured or infected, itreleases chemical alarm signals that promote dilation of bloodvessels at the injury site.

15. Reproduction in reptiles compares toreproduction in birds in that

A. both newly hatched birds and reptilesrequire parental care.

B. the eggs of both birds and reptiles haveprotective shells.

C. birds are oviparous, reptiles areovoviviparous.

D. both exhibit external fertilization.

E. male or female reptiles reproduceasexually; birds do not.

16. ______diseases are those abnormalconditions in which the bodyÃ¢â¬â¢s defensive cells fail to make theself versus the nonself distinction correctly, and attack thebodyÃ¢â¬â¢s own tissues.

A. Cancerous

B. Septic

C. Autoimmune

D. Nondiscrete

17. Most marine invertebrates areosmoconformers. This means that

A. the osmolality of their body fluids isequal to that of the osmoregulators who inhabit the sameenvironments.

B. the osmolality of their body fluidsfluctuates between being hypertonic to hyportonic depending on theseason and the tides.

C. the osmolality of their body fluids isnot the same as their seawater environment

D. the osmolality of their body fluids isthe same as their seawater environment and that their bodiescontain the same solutes as their surroundings

E. the osmolality of their body fluids isthe same as their seawater environment

18. Which of the following determinesgenetic (male or female) in mammals?

A. the acrosome of the sperm

B. the temperature of the developingfetus

C. the SRY gene on the Y chromosome

D. the genetic makeup of the parents

E. the Y chromosome contained in theegg

If you can please explain why and how yougot the answer. 5 star rating for correct answers only, I have theanswer sheet, and just want to double check.

jadesnake579

1. Select which of the following are mechanisms used by pathogens to avoid host defenses and to successfully colonize the host.

A. Producing siderphores to obtain iron from the host for growth

B. producing adhesins for damaging host cells

C. Avoiding IgA proteases for avoiding secretory IgA

D. Avoiding secretory IgA by rapid turnover of pili

E. Producing toxic substances to suppress host responses

2. People considered obese have a different normal flora in the gastrointestinal tract compared to people who are considered lean.

A. true

B. false

3. Which of the following is NOT a mechanism used by pathogens for avoiding or surviving phagocytosis?

A. Killing macrophages and neutrophils

B. Colonizing the phagocyte

C. inhibiting opsonization

D. Inhibiting phagocte chemotaxis

E. these are all methods of avoiding or surviving phagocytosis

4.Which of the following immune responses is best suited to prevent a virus from infecting a cell?

A. complement cascade

B. inflammation

C. Virus-specific antibodies

D. Fever

E. phagocytic cells

5. Which of the following is NOT a method used by pathogens for penetrating skin or mucous membranes?

A. Injection of effector proteins that induce endocytosis

B. Exploiting antigen-sampling processes

C. these are all mechanisms for penetrating skin or mucous membranes

D. Exploiting an injury

E. Production of endotoxin

6. Antibodies, which are produced as part of the adaptive immune response, can sometimes be damaging rather than beneficial. People suffering from an autoimmune disease called antiphospholipid antibody syndrome (APS) make antibodies that bind to phospholipids. Some of the signs and symptoms affected individuals experience are blood clots, stroke, heart attack, and kidney damage. What is the likely cause of these symptoms?

A. the anti-phospholipid antibodies cuse immune complexes that lodge in the affected organs

B. The person fails to make protective antibodies

C. The anti-phospholipid antibodies weaken certain organs that contain fat

D. the person makes antibodies that bind inappropriately to bacterial capsules, preventing phagocytosis of these cells

E. Cell damage caused by binding of these antibodies initates inappropriate coagulation events which inferfere with blood flow in affected organs.

7. Only Gram-positive bacteria produce exotoxins

A. true

B. False

8. Which of the following members of the normal microbiota inhibit the growth of Candida albicans?

A. Lactobacilus species

B. Staphylococci species

C. E. coli

D. Neisseria species

E. Propionibacterium species

9. Would an antibody response against the B subunit of an A-B toxin protect against the effects of the toxin?

A. yes. if antibodies bind to the B protion, the toxin can no longer bind to target cells and will thus not affect those cells

B. No, even if antibodies bindto the B portion of the toxin, it is the A portion that actually causes damage to the cell

C. This question cannot be answer. The immune system does not mount a strong response against proteins, so this situation is unlikely to occur.

D. Yes, if antibodies bind to the B protein, that portion of the toxin does not become activated, and thus does not damage the host cell

E. No, even if antiibodies bind to the B portion of the toxin, the toxin is still taken into the host cell by phagocytosis, damaging that cell

10. Please select the correct definition of balanced pathogenicity.

A. A host-parasite relationship in which the parasite persists in the host, causing maximal harm. The pathogen becomes more virulent while the host becomes increasingly susceptible.

B. A mechanism that allows bacteria to transfer gene products directly into host cells, inducing changes such as altering the cell's cytoskeleton structure

C. A generated balance in the microbiome that may be caused by taking antimicrobial medication. it generally helps the host maintain optimal health

D. A situation in which an abnormally high number of T-helper cells are stimulated, causing a massive release of cytokines.

E. A host-parasite relationship in which the parasite persists in the host while causing minimal harm. The pathogen becomes less virulent while the host becomes less susceptible

11. Bacteria may survive phagocytosis by

A. preventing encounters with phagocytes AND preventing fusion of two pathogosomes

B. avoiding recognition and attachment of lymphocytes AND lysinf the phagosomes

C. preventing fusion of the lysosome with the phagosome AND mimicking host molecules

D. lysing the phagosome AND mimicking host molecules

E. preventing fusion of the lysosome with the phagosome AND lysing the phagosome