PATH 3610 Lecture Notes - Lecture 2: Von Willebrand Disease, Pericardial Effusion, Pleural Effusion
16 Jun 2017
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Document Summary
Passing from solution of lesser concentration of solute to greater solute concentration, through a semi permeable membrane. Hydrostatic pr than oncotic pr- fluid into tissues. Hydrostatic pro. than oncotic pr- fluid out of tissues into vessel. Fluid that drains from the tissue into blood stream. Excess fluid being seen in many tissues (e. g. congestive heart failure) Tissue fluid in body cavities (pleural effusion, pericardial effusion) Changes in blood flow & body fluid characteristics. At venular end - hp>op so fluid remains in tissue as edema. Small amounts of fluids in the interstitum more protein molecules accumulate overtime so tissue colloid oncotic pr. Acute inflammation, acute allergic reaction, venous obstruction and lymphatic obstruction. Mechanical abnormality (valvular regurgitation, intracardiac shunting, restrictive heart disease) Resistance to forward flow (hypertension, aortic stenosis) Retention of salt and water output from left ventricle gfr renin aldo na resorption: vascular hydrostatic pr blood vol, vascular oncotic pr (dilute blood albumin)
