PATH 3610 Lecture Notes - Lecture 13: Lymph Node, Tracheitis, Cardiac Output

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Andrew Vice

Document Summary

There are more capillaries than blood in body. Capillary: gaps can open and close, cell has ability to shrink, endothelial cells damaged, blood will leak out, endothelial (inside the body, capillary sphincter regulates blood flow in that area. Lot of fluid membrane around heart = hydropericardium. Edema: can be inflammatory, increased permeability, effusion, can be non-inflammatory. Increased venous hydrostatic pressure: heart failure, postural edema (sitting for too long, reduced oncotic pressure, albumin is lost through wounds, kidney, malnourishment, hypoproteinaemia/hypoalbuminaemia, kwashiorkor (big belly due to malnourishment) Lymphatic obstruction (elephant feet: removal of lymph node. Increased total body water: sodium retention (renal failure) Circulatory disturbances: edema is one example, excessive sun exposure: skin peeling, increased blood flow. Hyperemia = more blood flows in all capillaries of the area (active) Congestion = reduced flow, buildup of capillaries (passive) Infarction = reduced flow of blood in region causing it to die (step 2 of ischaemia) End-artery systems = heart, brain, kidney (get infarction commonly)