PATH 3610 Lecture 4: PATH 3610; Unit 04

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Inflammation is nonspecific: skin and mucous membrane, physical barrier to foreign agents, cells are routinely sloughed from the surfaces of both foothold preventing organisms from gaining a, skin surface has a slight acidic ph to prevent growth of some organisms, mucus acts as a protective coating, cilia helps move foreign particles out of the respiratory tract, cough mechanisms helps to expel such material more forcefully. Characteristics of the immune response: all prevent foreign agents from gaining a: specificity reactivity is directed specifically toward the foreign agent, through recognition of antigens, memory specific antigen is remembered by the body after its initial exposure, recognized when encountered again, enhanced response during second exposure to antigen, amplification. Antigens: molecules which evoke an immune response when introduced into a host: large molecules, typically protein/polysaccharide, smaller molecules (haptens) can become antigenic if complexed with larger carrier molecules, foreign (extrinsic) antigens include infectious agents (i. e. bacteria, viruses, protozoa, fungi), transplanted foreign cells, etc.

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