PSYC 2330 Lecture Notes - Lecture 9: Kainate Receptor, Chemical Synapse, Ligand-Gated Ion Channel
31 Mar 2017
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Document Summary
Long term changes in synaptic strength = long-term potentiation. Neuronal activity can lead to long-term after-effects that alter the release of neurotransmitters, the anatomy of synapses and the sensitivity of postsynaptic terminals on a timescale of hours or days. Unlike the other forms of synaptic enhancement, ltp: It is mediated by pre- and postsynaptic changes: lasts longer, requires the activation of special receptors. 3: some changes are anatomical, ltp is heterosynaptic, ltp is associative. When there is a secret in the brain that is activated, and the activity keeps going in a circuit for an amount of time (keeps being activated over and over again), the circuit will change. Ltp allows the circuit to go from electrical to anatomical stable stage --- consolidation. 4 neurons - 3 feed into a fourth neuron. Principal excitatory neurotransmitter of the brain & spinal cord. Four types of receptors: nmda receptors (ionotropic, ampa receptors (ionotropic, kainate receptor (ionotropic, mglur (metabotropic)
