PSYC 2410 Lecture Notes - Lecture 1: Substantia Nigra, Nmda Receptor, Kainate Receptor

• School: University of Guelph
• Department: Psychology
• Course: PSYC 2410
• Professor: Elena Choleris

Document Summary

Deliberate genetic manipulations (gene knockout and knock in) Agonist: a drug that facilitates the effects of a particular neurotransmitter. Antagonist: a drug that inhibits the effects of a neurotransmitter. Drug increases the synthesis of neurotransmitter molecules (e. g. , increasing the among of precursor) Drug increases the number of neurotransmitter molecules by destroying degrading enzymes. Drug increases the release of neurotransmitter molecules from terminal buttons. Drug binds to autoreceptors and blocks their inhibitory effect on neurotransmitter release. Drug binds to postsynaptic receptors and either activates them or increases the effect on them of neurotransmitter molecules. Drug blocks the deactivation of neurotransmitter molecules by blocking degradation reuptake. Drug blocks the synthesis of neurotransmitter molecules (e. g. destroying synthesizing enzymes) Drug causes the neurotransmitter molecules to leak from the vesicles and be destroyed by degrading enzymes. Drug blocks the release of the neurotransmitter molecules from terminal buttons. Drug is a receptor blocker; it binds to the postsynaptic receptors and blocks the effect of the neurotransmitter.