PSYC 3410 Lecture Notes - Lecture 7: Body Dysmorphic Disorder, Neuropeptide Y, Ghrelin

• School: University of Guelph
• Department: Psychology
• Course: PSYC 3410
• Professor: Elena Choleris

Document Summary

N e u ro s c i e n c e i i. F e b rua ry 4 , 2 0 1 6. Adipose tissue ob gene leptin. Homozygous ob/ob mice treatment with leptin (lose weight and get leaner. Ob/ob humans mutated gene is not really that common in humans, but those that do respond very well to leptin. Second mutation: db/db (leptin receptor: deicient leptin receptor ob-r, will not respond to treatment with leptin but are obese. O b e s i t y i n s u l i n r ec e p to r- d ef i c i e n t m i c e. Even if the receptor for insulin in the body is ine, if it"s bad in the brain you"ll still have an overweight animal this says it"s very dependent on the brain. Pancreas insulin blood body + brain.