ANSC 313 Lecture Notes - Lecture 7: Animal Breeding, Cleft Lip And Cleft Palate, Allele Frequency
Which Teratogen?!
dam hit by a car at 10 days gestation!ā¢
broken pelvis!ā¢
anesthesia for 6 hours!ā¢
pain medication for three weeks!ā¢
one pup of the 12 : had a cleft lip!ā¢
doesn't eļ¬ect all members of a littler equally!ā¢
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"Phenocopy"!
"allergy" is a broad term!ā¢
does it represent multiple disorders?!ā¢
multiple causes?!ā¢
variable expressivity of one trait?!ā¢
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Inheritance patters!
single gene!ā¢
chromosomal!ā¢
multifactorial!ā¢
teratogenic!ā¢
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Population Genetics!
allele frequencies of a population of animals!ā¢
i.e. what is the frequency of the polled allele (P):!ā¦
in Canadian Charolais?- accepted in Canada!ā£
in french Charolais? - not accepted in french so would have a much lower frequency!ā£
in Charolais world wide? - harder to get!ā£
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Species!
a discrete, reproductively deļ¬ned system of populations with a common evolution!ā¢
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Breed~ race!
a population distinguishable from another of the same species by frequencies of genes, ā¢
chromosomal variation, or hereditary phenotypic characteristics!
NOTE: a breed is subject to certain criteria by law in Canada under Animal Pedigree Act, i.e. ā¢
breed standard, " registration"!
parentage veriļ¬cation is a breed association`s right under this act!ā¦
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in many species , some genes are "ļ¬xed" meaning ALL animals are homozygous for same ā¢
allele!
i.e all angus are polled, "P/P"!ā¦
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Hardy-Weinberg Equilibrium!
allele A a !ā¢
Gene frequency p q!ā¢
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%if Aa X Aa!
1AA : 2Aa : 1aa!