BIOL 120 Lecture 5: BMSC 220.3 Notes for Topic 5
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Bmsc 220. 3 cell biology. Textbook readings (5th edition: chapter 6, pages 201- 216. Dna replication: dna polymerases: In higher eukaryotes, origins may be defined by chromatin structure rather than. The resulting gap is filled by newly synthesized dna, using the undamaged complementary strand as a template. In base- excision repair, specific types of single damaged bases are removed from the dna molecule. Dna polymerases: dna polymerases are a group of multi- subunit enzymes that catalyze the synthesis of. Each okazaki fragment is 1000- 3000 bp long. Replication fork: leading and lagging strands. For this, no 3" - oh is required. Initiation of okazaki fragments with rna primers. Removal of rna primers and joining of okazaki fragments. Action of helicases and single- stranded dna- binding proteins. Action of topoisomerases during dna replication. Model of the e. coli replication fork. Origin of replication in circular e. coli dna. A molecule against which an antibody is directed.
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