NUTR 120 Lecture Notes - Lecture 17: High-Protein Diet, Portal Vein, Chymotrypsinogen

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13 Mar 2017
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All consumed protein can be used for energy (4 kcal/g) *protein is the most expensive form of energy for body. (body would rather use fat + carb for energy) In stomach: hcl (cid:858)denatures(cid:859) protein, protein (pepsin) peptides (small a/a chains) In small intestine (major site for digestion by enzymes intestinal enterokinase) pancreas secretes pancreatic pre-enzymes- trypsinogen & chymotrypsinogen: trypsinogen (intestinal enterokinases) trypsin. Can also cleave peptides into smaller peptides: various intestinal pre-peptidases (trypsin) various peptidases. Cleave of aa 1 by1 from dietary peptidases: chymotrypsinogen (trypsin) chymotrypsin. This cleave peptides into smaller peptides: these(di & tri peptides) are broken down into individual aa + tri- & di- peptides. Portal vein: pass through intestinal cell to portal vein & into the liver (smolin fig. Overall scheme: (aa coming from liver) aa from diet (exogenous) aa from liver breakdown (endogenous) Aa (cid:862)pool(cid:863) in (cid:272)ell [(cid:271)ody (cid:272)ell eg liver] (cid:894)1(cid:895) synthesis of body proteins (enzymes, antibodies) (2) .

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