NUTR 120 Lecture Notes - Lecture 23: Hemolytic Anemia, Vitamin K, Phylloquinone
Document Summary
Antioxidant in fat rich regions of the body. Vitamin e is distributed widely to all body tissues. Vitamin e deficiency: hemolytic anemia: damage to cell membranes (cid:862)lysis(cid:863, lung tissue damage especially in smokers, retinal membrane with age can lead to cataracts, free radical damage to the protein in retina. High levels may interfere with proper blood clotting causing hemorrhaging. In 1929 a fat soluble factor was found to be necessary for blood clotting (vit k) In 1939, a version of vit k (phylloquinone) was discovered found in alfalfa and green leafy veggies. Vit k2 (menaquinone) found in meat, eggs, cheese and colon microbes was discovered. ** not stored well: blood clotting, bone metabolism, kidney function, calcium absorption from gi tract. Long term antibiotics can cause decrease in colonic microbe vitamin k production. Excess oral vitamin k supplements may interfere with anticoagulant drugs. Sodium, potassium, chloride, (electrolytes) calcium, magnesium, phosphorus, and sulfur.
