NUTR 120 Lecture Notes - Lecture 7: Atheroma, Coronary Circulation, Foam Cell
Document Summary
Single mono-layer of cells (endothelial tissues: years of excess dietary saturated and trans fats, and cholesterol = increase in ldl and tc, cannot have atherosclerosis with an increase in ldl. Foam cells are an accumulation of macrophages taking on excess amounts of oxldl, and creates larger portions of arterial plaque: monolayer of cells means that you can"t go in and scrub away the plaque. Summary: roles of ldl & hdl in chd. Ldl: if not take up by the liver, accumulates in blood. Sort of, through drugs, but the risk of chd remained the same despite the increase in hdl shows that the process is way more complicated than we know. Avoid dietary supplements that claim to raise hdl (only if you"re overweight) lose weight; for every 10 lbs of weight loss, hdl increases 2 mg/dl (for every 1 mg/dl increase in hdl, chd risk decreases 2-3% Limit your dietary intake of sugars and refined carbohydrates (*metabolic syndrome)
