BIOL130 Lecture Notes - Lecture 10: Intermediate Filament, Neuroglia, Nuclear Membrane
12 Aug 2017
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Document Summary
It is a network of fibres forming scaffolding within cytoplasm. Determines cell shape and the position of organelles. Allows movement of organelles / components within cells. It is dynamic and constantly being reorganized. Both prokaryotes and eukaryotes have a cytoskeleton. Ropey fibres that go all through the cytoplasm. Anchored at the junctions (desmosomes) that are located between neighbouring epithelial cells, provides a cohesion between epithelial sheets. If the epithelial layer was stretched the intermediate filaments will keep the cells held together. Intermediate filaments consist of long, twisted strands, strands are staggered. Strands are made of long fibrous proteins that have the -helical structure for the rod with a globular n-terminal head and a globular c-terminal tail. Central rod are all similar in size and amino acid sequence. Classes of intermediate filaments i c m s a p o t y. Vimentin: in connective tissue, muscle cells and neuroglial cells.
