BIOL130 Lecture Notes - Lecture 8: Chemical Polarity, Lipid Bilayer, Dehydration Reaction

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Biol 130 Worksheet Unit 2b Part 2
Cellular Chemistry - Biomolecules Part 2 Nucleic Acids, Carbohydrates, Lipids
Terms to Learn:
adenosine triphosphate (ATP)
amphipathic
anti-parallel
base, base pair (bp)
cholesterol
cis, trans
complementary, 5’, 3’
flip / flop (!)
fructose
glycogen
hexose, pentose
hydrophilic, hydrophobic
isomers, structural vs stereo
lipid bilayer
major & minor groove
micelle
nucleotide, nucleoside
NTP
ribose, deoxyribose
starch
stereo-, stereochemistry
glyco-
hydro-
oligo-
petido-
-lysis
-mer
-ose
Match:
1) an activated nucleotide that is ready to participate in a polymerization reaction to form DNA or RNA
2) a nucleotide (nucleoside triphosphate) best known for its role in cellular energy metabolism
3) molecules that have the same molecular formula but different structures, eg functional groups bonded to different
carbons
4) a branch of chemistry dealing with the spatial arrangement of atoms that give rise to the three-dimensional shapes of
molecules
5) a nonpolar molecule or part of a molecule that cannot form energetically favourable interactions with water molecules,
and therefore does not dissolve in water
6) a molecule that is hydrophilic / polar at one end and hydrophobic / nonpolar at the other.
7) a structure formed by amphipathic molecules in aqueous solution arrange themselves in a single-layered sphere, with
hydrophobic tails oriented inward
8) a lipid with a characteristic four ring structure that is an important component of the plasma membrane of animal cells
9) transfer of phospholipids between inner and outer membrane leaflets
Questions:
1. Label the major parts of the nucleotide to the right.
Indicate with an arrow where the phosphate group of the next
nucleotide group would attach.
Number the carbons of the pentose.
Is this a purine or a pyrimidine? How do you know?
Would this be used to build DNA or RNA?
2. Number the carbons in the glucose molecule to the right (each
unlabelled corner of the ring represents a carbon). Circle the atoms that
will be removed by a dehydration reaction.
3. Examine the diagrams below, showing segments from two carbohydrates. One is cellulose, the other is glycogen.
Which is which? How can you tell?
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Document Summary

Cellular chemistry - biomolecules part 2 nucleic acids, carbohydrates, lipids. Biol 130 worksheet unit 2b part 2 flip / flop (!) fructose glycogen hexose, pentose hydrophilic, hydrophobic isomers, structural vs stereo lipid bilayer. Terms to learn: adenosine triphosphate (atp) amphipathic anti-parallel base, base pair (bp) cholesterol cis, trans complementary, 5", 3". Ntp ribose, deoxyribose starch stereo-, stereochemistry glyco- hydro- oligo- petido- Questions: label the major parts of the nucleotide to the right. Indicate with an arrow where the phosphate group of the next nucleotide group would attach. Would this be used to build dna or rna: number the carbons in the glucose molecule to the right (each unlabelled corner of the ring represents a carbon). Circle the atoms will be removed by a dehydration reaction: examine the diagrams below, showing segments from two carbohydrates. How can you tell? that: the start of the coding region for the human -globin gene reads 5"-atggtgcac-3".

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