CS370 Lecture 6: Unit 6 Least Squares (complete)

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Goal: to see how the problem of least-squares crops up in data analysis. Functional mri is able to pick up on slight brightness changes due to the concentration of oxygenated blood caused by neurological activity. Active brain regions appear between 1% and 4% brighter. To find out what part of the brain is responsible for different types of processing, give the desired stimulus in an on/off manner and look for corresponding fluctuations in the brightness. eg. stimulus. The fmri signal for a given pixel can be decomposed as signal = brain activation + baseline intensity. This is how bright the pixel would be without any other influences. We can measure their lung volume during the scan, so we know the basic form of this component. The heart beat causes a similar oscillation, but at a higher frequency. We can also monitor the patient"s heart beat.

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