KIN104 Lecture Notes - Lecture 12: Muscle Hypertrophy, Myosatellite Cell, Gene Therapy
28 Jan 2015
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Document Summary
Physiology: science of the function of living systems. Pathophysiology: study of the change of all these functions: muscle disease apoptosis (cell death) Muscle adapts to meet the habitual level of demand placed on it; decrease muscle use (prolonged bed rest limb casting, space flight) Muscle wasting and dysfunction occur during aging, inactivity and disease. Aging, inactivity, cardiovascular diseases, respiratory diseases (copd), muscular. Because understanding specific adaptions we can develop strategies to diseases, cancer, brain injury, hiv/aids. Why is this important? maintain/improve function of the muscle. Levels of investigation: whole body, organ/tissue, cellular, molecular, gene. Muscle fibre: a cell type in your body that helps you move. Fluorescence technology: used to figure out how cells work. Dna from jellyfish placed into the gene code of another organism now the organism has the proteins of the jelly fish (mice with fluorescent genes) Satellite cells play a role in muscle growth an maintenance.
