KIN217 Lecture Notes - Lecture 12: Srb, Rna, Synagogue
28 Apr 2018
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Professor
Lecfure 12 - ATP SScrthose
chop+er 2\ - Proton Motrve F>cce.
. Resprra.sorne pumping o{ e.\ec€ro^s fesu\+s in ^n :l-$ P!ttg!:
r-; chcmrco\ grodtent d e.tect$ca\ gradie.nE
'uie +hts e-n€rgy +o mo.Ke. ArP
+ \s *he rnernbran€ ?rote\n +ho,t cagtrlr€S *he groton
ATP
Arf Syntharc-
.Tw o compon€nts
+ Fo corngonent \s
'con{o\rrE +he
b g, component rn+o {he'
'con+q\ns +h€ ac+iV€ 'srt€'
inner fnttochorv\riq\ rne'rnbrgtg
' f, A fo conneck€d bJ ! subvn,t * an extern4\ co\um
+ y Srb,.rnrt haS unrque shc.pe hot rnb<rocts uorbh Yee' f S"htnntS
u-reo.ch Subunr* is ofr CrCtrr{e \rt
4A Sub,;nrts, lst{ctc +h€ p subunrts from eoch orthe'c
s lh p subunrt
f, Sv.bv,rrF rn $etar\
I-1 Juuv' " '
'r\e 3 ca*a.\v*\c B stbuntts €xtsl tn 3 A'tterc:*- t::1,:::1";:t-O:f:Tt,,ll^l sub':n't
I; #$:J;;"**,*, "o", b, o or be cc\ec.'ect {rorn the $ subunr.
-\ ..^ rr-^ R q.rb,.lOtk
; :|,[-|iorff\ ) nuc\€o*deS o.re kngqe.\ in rrhe g sub.rotk
o.
;;:i"* i".* --* ATP ts sgnthesize<: {rorn AoP {" Pi
. P(I.P s(jr\ e \s q smq\\ Yno\ecu\o'c mo*oc
. can J=".ua +he ro+at'io^ o+ +he y subunr* direc{\r1
.ctoned"{S9cY Subunrts q{*ached +9 o 3\oss S\rde o\\ot^l {novemenL
oQ *he \ Subunr! {o b,e Visuq\tz€d
l-,) USe ATP hgdrofySis *o drrVe (notor (co.nkec c\ocfrorse)
L+ prtahons tottt Sprn th. c\oc.Kwrrs€ *o mo'lie ATP
PYct rr.' Flclri Tht cugh F-o
" Subvnrt e" *ouches th\e c rtng
. Subvnttcu
+ 2 chqnne\S +-l-ro{ reqch ha\fwcty lnto the a. subtrn\k (€xt€ns\on o{ a1ueo.:S sgace)
. one ho\{ channe\ oP€ns to the tnt€rrne:fitbr^trns- \Pa( e
' or€ ha\Q chonne\ gqgr\s \o'l.he. iT\cttrrx
t
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+ asPartot€
t-t Subun,g .o5 *he mcve \nto n$Po\ar c€g\on oQ
L+ groton 3rudrent dictoleS dr(€c.1.r",,f\ o( Sprn
emhedc\ed in {ln<,
ii66n7tronr'et hr*ochondria\ mostrtX
tn VerlebrarteS
'i"",a"" of sgot e.x?o:€d +o ha\f chorrne\S {or each Subr;nr\
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