BIOL 200 Lecture Notes - Lecture 4: Secretory Protein, Clathrin, Pinocytosis
Document Summary
Exocytosis: constitutive secretory (default) & signal-mediated diversion to secretory vesicles. Lipids (membrane component) important for cell expansion, lipid biosynthesis (replace old lipids with new ones) & asymmetry. For more specialized process of rapid release of proteins and lipids due to a signal (on demand) You can get an idea of how fast they are moving (kinetics) and where they are going to. Proteolytic cleavage they get cleaved in the vesicle on their way to the lysosome. If it"s cleaved in the golgi, that could be very bad for the surrounding environment. Made up of hydrolases (anything that can break things apart) Vacuoles (instead of lysosome) = where things are degraded in plant cells. Mostly due to buildup of toxic byproducts. Macrophages, neutrophils, dendritic cells: ingest cellular debris. Specialized process in only a few cell types. Non-selective about what they are bringing in (just happens) Doesn"t need coated vesicles (happens more freely and easily)