BIOL 201 Lecture Notes - Lecture 27: Atp Synthase, Antimycin A, Oligomycin
Document Summary
Atp synthase inhibitors / h + gradient inhibitors (uncouplers) Electron donors (e. g. nadh) gives the energy to transport electrons across the etc. Matrix ph rises (outer membrane is porous) = greater ph gradient harder to pump h + across etc stop. When h + transported by the atp synthase is blocked, eventually the etc shuts down . As the etc works, the h + gradient builds up in the ims continuously because h + cannot re-enter the matrix via the atp synthase. At some point there is not enough energy from the oxidation of e donors to etc to transport h + against the intensified h + gradient e transfer stops. Electron transfer and h + transport of etc and atp synthesis are connected = coupled . In the presence of cyanide , o 2 cannot be converted to h 2 o. Plants as primary producers are able to convert light into stored energy (sugars)!
