CAPS 390 Lecture Notes - Lecture 8: Anaphylaxis, Salivary Gland, Mast Cell

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Derived from mesenchymal stem cells: fibroblasts, adipocytes, and pericytes. Derived from hematopoietic stem cells: mast cells, macrophages, plasma cells, and numerous white blood cells. Prominent in extensive rer and golgi and nucleus contains abundant chromatin. Pericytes: stabilize small blood vessels in connective tissue and are contractile. Numerous vacuoles, lysosomes endosomes and vesicles in cytoplasm. Derived from monocytes that are generated in the bone marrow. Cells that initiate inflammatory responses by responding to pollens, venoms and foreign proteins. Hyper activation/sensitivity of mast cells contribute to hay fever and anaphylactic shock. Clockface nucleus with alternating areas of euchromatin and heterochromatin. Unicellular glands: single secretory cells embedded in a surface/lining epithelium; Multicellular glands: clusters of secretory cells surrounded by ct; secrete into a duct. Multicellular glands: duct system: simple gland ducts do not branch. Compound gland-ducts branch: shape of secretory unit at end of ducts-tubular- shaped like a tube,

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